MAT is Not Just Medication

Understanding the Full Scope of Addiction Treatment and Recovery

A guest blog provided by Mark Pirner, M.D., Ph.D.

MAT is not just medicationI am concerned that the term medication-assisted treatment (MAT) – using methadone, buprenorphine, naltrexone – might be perceived outside of the addiction community as a stand-alone treatment for opioid use disorder. The implications are important because behavioral therapy, psychosocial change, and earnest personal work are all critical cornerstones of addiction treatment and recovery. It is a disservice to the community of stakeholders (including policymakers, government officials, criminal justice workers, insurance providers, healthcare providers, patients, and their loved ones) to allow the perception that medications alone are enough for recovery to happen.

MAT Historically

Historically, the term MAT was coined at a time when limited or no FDA-approved medications were available for the treatment of opioid use disorder. MAT as a descriptor was intended to distinguish opioid use disorder treatment programs that incorporated medical therapy (e.g., methadone) in addition to behavioral modification and psychosocial intervention. The intent was not to replace behavioral and psychosocial treatments with pharmacological treatment(s), but rather to use both as complementary to each other. Pharmacology by itself was never intended to be a stand-alone treatment for substance use disorder (SUD). Guidelines today remain clear that treatment including behavioral/psychosocial intervention is essential for SUD treatment.

Read more about MAT: What is Medication Assisted Treatment (MAT) and Other Common Questions About This Increasingly Popular Treatment Approach

Should We Be Using TAM?

Perhaps a more appropriate descriptor for using adjunctive medication(s) in the treatment of SUD would be something like treatment-assisting medication or treatment-assisting modalities (TAM). This more accurately keeps the focus on the fact that treatments of all shapes and sizes can be tailored to patients and their providers with behavioral and psychosocial change at the core, whether with or without prescription medications or other modalities (such as treatment apps) that continue to be developed. This could also avoid the potentially unintended consequence of limiting access to newer or different treatment choices. For example, naloxone is a life-saving treatment that may not neatly fit into MAT since it is not a SUD maintenance therapy, yet it is a critical tool that reduces the morbidity and mortality of opioid overdose. Another example is if patients/providers are ‘forced’ through treatment algorithms or unwanted steps based on prior authorization criteria, not central (or potentially necessary) to their recovery plan.

For more information on addiction terminology, accuracy and stigma, watch this recent presentation from the 2019 SMART Recovery National Conference by Richard Saitz, M.D.

Main Point

Recovery is a holistic process that is worked through in stages. It is hard, it is lifelong, and it is not accomplished through medication alone. Further, hopefully and undoubtedly, new treatments will be developed, whether medication-based, app-based, behavioral-based or beyond our current imagination. It doesn’t really matter what we call them, and they still must meet the rigorous requirements of FDA-approval. But, when this is the case, they should be made available, and our terminology should be adjusted accordingly to avoid unintentional consequences.

About the author: Mark Pirner, M.D., Ph.D. is a senior medical director at US WorldMeds (, where he leads their medical affairs opioid withdrawal treatment portfolio. Dr. Pirner attended medical school at the University of Minnesota and, completed internal medicine residency at Duke University Medical Center and endocrinology fellowship at the National Institutes of Health. US WorldMeds is a wholly owned specialty pharmaceutical company based in Louisville, Kentucky, committed to raising awareness of opioid withdrawal syndrome and its treatment.

See other guest blog posts by Dr. Pirner: 

02 Oct 2018

What is Medication Assisted Treatment (MAT)?

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The 2023 Richard Saitz Memorial Lecture
14 Apr 2023

The 2023 Richard Saitz Memorial Lecture

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21 Feb 2012

Self Control Strategies To Prevent Relapse

Read More